发明名称 Water-soluble complexes of water-insoluble pharmaceutical compounds and preparation thereof
摘要 A method for increasing the water-solubility of highly insoluble organic compounds by forming a novel complex product from the reaction between the organic compound and an oligomer of vinylpyrrolidone. The complex is highly stable and results in solubilities of the organic compounds in excess of 25-fold.
申请公布号 US4920145(A) 申请公布日期 1990.04.24
申请号 US19880161881 申请日期 1988.02.29
申请人 GAF CHEMICAL CORPORATION 发明人 CHO, JAMES R.;SMITH, TERRY E.;COTTRELL, IAN W.
分类号 A61K9/08;A61K31/135;A61K31/155;A61K31/18;A61K31/34;A61K31/405;A61K31/63;A61K47/22;A61K47/32;A61K47/48 主分类号 A61K9/08
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