| 摘要 |
Polymeric affinity membranes comprise a precursor filtration membrane and a plurality of reaction sites provided on the surface of the membrane selective to binding a specific biological material. A process for the preparation of such affinity membranes includes the steps of providing a copolymer compatible with a water insoluble polymer matrix and having a plurality of hydroxyl groups, activating the hydroxyl groups and a compound selected from the group consisting of organic compounds reactive with a hydroxyl group in the presence of water miscible solvent to provide a derivatized copolymer containing active adducts, forming a solution of the derivatized copolymer and the polymer matrix to form a polymer blend solution, casting the polymer blend solution and, quenching the cast polymer blend solution in water. A process for selectively removing biological materials from fluids includes the step of passing the fluids over an affinity membrane which comprises a precursor filtration membrane and a plurality of reaction sites provided on the surface of the membrane selective to binding a specific biological material. |
