| 摘要 |
<p>Heparin and low molecular weight derivatives of heparin lacking anticoagulant activity are effective in interfering with the life cycle of HIV. Cells exposed to heparin or its low molecular weight derivatives one hour before or after challenge with HIV showed no evidence of viral infection when examined four to six days post HIV challenge. Control cells similarly challenged with HIV showed 100 % HIV infection six days post HIV challenge. Cells challenged with HIV as much as 48 hours before exposure to heparin or its low molecular derivatives showed little evidence of HIV multiplication and evidenced healthy morphological features.</p> |
