发明名称 .BETA.-D-PHENYLTHIOXYLOSIDES, THEIR METHOD OF PREPARATION AND THEIR USE AS THERAPEUTICALS
摘要 The present invention relates, by way of novel industrial products, to the .beta.-D-phenylthioxyloside compounds of the formula (I) in which: - X represents a sulfur atom or an oxygen atom; - R1, R2 and R3, which are identical or different, each represent a hydrogen atom, a nitro group, a cyano group, a group -CO-R (in which R represents a C1-C4 alkyl group or a trifluoromethyl group), an amino group, an acetamido group (NHCOCH3), a C1-C4 alkoxy group, a trifluoromethyl group or a phenyl group substituted by one or more cyano, nitro or trifluoromethyl groups, it being possible for X1 and R2, taken together, to form, with the phenyl group to which they are bonded, a .beta.-naphthalenyl group which is unsubstituted or substituted by one or more cyano, nitro or trifluoromethyl groups; and - Y represents the hydrogen atom or an aliphatic acyl group. These compounds are useful as therapeuticals, especially as venous antithrombotics.
申请公布号 CA2000769(A1) 申请公布日期 1990.04.18
申请号 CA19892000769 申请日期 1989.10.16
申请人 FOURNIER INNOVATION ET SYNERGIE 发明人 SAMRETH, SOTH;MILLET, JEAN;BELLAMY, FRANCOIS;BAJGROWICZ, JERZY;BARBEROUSSE, VERONIQUE;RENAUT, PATRICE
分类号 C07H5/02;A61K31/70;A61K31/7024;A61K31/7028;A61K31/7034;A61P7/02;C07C323/09;C07C323/62;C07C333/04;C07H5/10;C07H13/00;C07H13/04;C07H15/14;C07H15/203;(IPC1-7):C07D335/02;A61K31/38 主分类号 C07H5/02
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