| 发明名称 |
Enzymatic preparation of 3',4'-anhydrovinblastine |
| 摘要 |
3',4'-anhydrovinblastine, a precursor of the anti-tumor alkaloids vincristine and vinblastine, is prepared by the enzymatic coupling of catharanthine and vindoline using an iron-containing compound such as peroxidase optionally in the presence of a peroxide. Substantially enhanced yields are obtained.
|
| 申请公布号 |
US4918011(A) |
申请公布日期 |
1990.04.17 |
| 申请号 |
US19860893018 |
申请日期 |
1986.08.04 |
| 申请人 |
ALLELIX BIOPHARMACEUTICALS INC. |
发明人 |
GOODBODY, ANNE E.;TSUYOSHI, ENDO;VUKOVIC, JOHN;MISAWA, MASANARU |
| 分类号 |
C07D519/04;C12N9/08;C12P17/18 |
主分类号 |
C07D519/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
