摘要 |
The invention is generally concerned with isoindolinyl-alkylpiperazine compounds generally characterized by the formula <IMAGE> (I) wherein X is halogen or trifluoromethyl; n is an integer ranging from 2 to 5; Y is <IMAGE> (a) <IMAGE> (b) <IMAGE> (c) <IMAGE> (d) in which R1 is hydrogen, halogen, lower alkyl, lower alkoxy, trifluoromethyl, cyano; R2 is hydrogen, halogen, lower alkyl, lower alkoxy; and R3 is hydrogen, cyano. These compounds are useful as diuretic and/or antihypertensive agents. |