发明名称 |
METHOD OF MAKING LIPOSOMES WITH IMPROVED STABILITY DURING DRYING |
摘要 |
A composition and method are provided for the making of cholesterol containing phospholipid liposomes such that when dried and then reconstituted, the liposomes retain their structure and size distribution as well as substantially all of the material that was originally encapsulated, and they behave biologically in a normal fashion. The cryoprotective agents are used in the aqueous medium to hydrate the phospholipid(s) and are a combination of at least one sugar and at least one protein, polypeptide, and/or oligopeptide.
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申请公布号 |
CA2000219(A1) |
申请公布日期 |
1990.04.05 |
申请号 |
CA19892000219 |
申请日期 |
1989.10.05 |
申请人 |
VESTAR, INC. |
发明人 |
SCHMIDT, PAUL G.;FUJII, GARY |
分类号 |
A61K9/127;A61K47/26;A61K47/42;B01J13/02;(IPC1-7):A61K9/127;A61K49/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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