发明名称 METHOD OF SYNTHESIS OF ALPHA OLIGORIBONUCLEOTIDES AND COMPOUNDS USEFUL FOR THE METHOD
摘要 <p>The invention concerns a method of synthetizing alpha oligoribonucleotide compounds in which synthesis is carried out with phosphoramidite on a solid support, as well as compounds useful in said method and the compounds obtained. According to the invention, protected alpha ribonucleoside monomers, substituted by phosphoramidite groups in the 3' position, are assembled, the hydroxyl function in the 2' position of the ribose of said monomer being protected by the Ctmp or TBDMS group.</p>
申请公布号 WO1990003381(A1) 申请公布日期 1990.04.05
申请号 FR1989000303 申请日期 1989.06.15
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