发明名称 A method of sensitizing multidrug resistant cells to antitumor agents.
摘要 <p>A method for sensitizing multidrug resistant cells to antitumor agents comprising contacting multidrug resistant cells, with an effective amount of a compound of the formula &lt;CHEM&gt; wherein n is 1, 2 or 3, X is CF3, -O-CH3, Br, I, Cl, H, W and S-CH3 and R&lt;1&gt; and R&lt;2&gt;, independently of each other are -CH3-CH2-CH3, CH2CH2OHCH2OH, or NR&lt;1&gt; R&lt;2&gt; form a ring &lt;CHEM&gt; wherein R&lt;3&gt; is -CH3, CH2-CH3,-H, CH2OH and CH2CH2OH. t</p>
申请公布号 EP0361485(A2) 申请公布日期 1990.04.04
申请号 EP19890117994 申请日期 1989.09.28
申请人 YALE UNIVERSITY 发明人 HAIT, WILLIAM, N.;FORD, JAMES M.
分类号 A61K31/00;C07D335/20;A61K31/38;A61K31/445;A61K31/495;A61P31/04 主分类号 A61K31/00
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