| 摘要 |
Methods are provided for producing super-agonist hormones, which hormones are those having the common alpha subunit of the gonadotropins, generally comprising the transformation of host cells with recombinant DNA comprising a first DNA sequence coding for an alpha subunit from an equine animal species and a second DNA sequence coding for a beta subunit from a non-equine species. The preffered hormone comprises an equine alpha subunit and a bovine, porcine or human beta subunit of LH, FSH, CG or TSH and exhibits a greatly increased activity. |
