发明名称 BICYCLIC CARBOXAMIDES,PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 The present invention provides compounds of the general formula (I) which inhibit the aggregation of erythrocytes or thrombocytes <IMAGE> (I) wherein A is hydrogen or C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, benzyl or C3-C7-cycloalkyl radical, B is hydrogen, R1 is a C1-C6-alkyl, C2-C6-alkenyl or C3-C7-cycloalkyl radical, R2 is a C1-C6-alkyl, C2-C6-alkenyl, C3-C7-cycloalkyl, C1-C6-alkylcarbonyl, C1-C6-alkoxycarbonyl, aminocarbonyl or hydrazinocarbonyl radical, or R1 and R2, together with the carbon atom to which they are attached, form a C3-C7-cycloalkyl ring, n is 0, X is a valency bond or a C1-C6-alkylene radical, R3 is a carbocyclic aromatic ring, which may be substituted; and the tautomers, optically-active forms and physiologically acceptable salts thereof with organic and inorganic acids.
申请公布号 ZA8904236(B) 申请公布日期 1990.03.28
申请号 ZA19890004236 申请日期 1989.06.05
申请人 BOEHRINGER MANNHEIM GMBH. 发明人 DR WOLFGANG VON DER SAAL;DR ALFRED MERTENS;DR ERWIN BOEHM
分类号 A61K31/40;A61K31/403;A61K31/404;A61K31/41;A61K31/42;A61K31/425;A61K31/44;A61K31/4427;A61K31/47;A61K31/50;A61P7/02;C07D209/34;C07D209/96;C07D215/48;C07D221/20;C07D401/12;C07D403/12;C07D405/12;C07D413/12;C07D417/12;C07D471/04 主分类号 A61K31/40
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