发明名称 |
REPLICATIVE RNA-BASED AMPLIFICATION DETECTION SYSTEMS |
摘要 |
This invention relates to the use of functional reporter molecules in the detection and measurement of nucleic acid sequences in a sample, as a determination, for example, of pathogenic disease existence or potential. The invention is predicated on the utilization of a transcription step between the production of an appropriate reporter molecule and replication based amplification in order to increase the number of detectable species as an indirect reference to target nucleic acid sequence. |
申请公布号 |
WO9002819(A1) |
申请公布日期 |
1990.03.22 |
申请号 |
WO1989US03833 |
申请日期 |
1989.09.06 |
申请人 |
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES |
发明人 |
CHU, BARBARA, CHEN, FEI;JOYCE, GERALD, FRANCIS;ORGEL, LESLIE, ELEAZER |
分类号 |
C07H21/00;C12Q1/68;C12Q1/70;(IPC1-7):C12Q1/68 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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