发明名称 Carbazate derivatives, their production and use.
摘要 <p>There are provided carbazate derivatives of the formula: R&lt;1&gt;-N=CH-NHNH-R&lt;2&gt; wherein R&lt;1&gt; is a heterocyclic group; and R&lt;2&gt; is an esterified carboxyl group, and their salts, which are useful as AGE-formation inhibitory agents. The derivatives or the salts can be produced by reacting compounds of the formula: R&lt;1&gt;-N=CH-R&lt;3&gt; wherein R&lt;1&gt; is a heterocyclic group; and R&lt;3&gt; is a lower alkyl group, with a carbazic acid ester or its salt.</p>
申请公布号 EP0359112(A2) 申请公布日期 1990.03.21
申请号 EP19890116469 申请日期 1989.09.06
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 SOHDA, TAKASHI;IKEDA, HITOSHI;MOMOSE, YU
分类号 C07D237/20;A61K31/33;A61K31/415;A61K31/4184;A61K31/42;A61K31/421;A61K31/425;A61K31/426;A61K31/433;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4418;A61K31/47;A61K31/472;A61K31/496;A61K31/505;A61K31/517;A61P3/08;A61P3/10;A61P9/10;A61P13/02;A61P15/00;A61P27/02;A61P27/12;A61P43/00;C07C281/02;C07D213/74;C07D215/38;C07D217/22;C07D231/38;C07D235/30;C07D239/42;C07D277/42;C07D239/84;C07D261/14;C07D263/48;C07D277/20;C07D285/04;C07D285/08;C07D285/12;C07D285/135;C07D521/00 主分类号 C07D237/20
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