Diuretic factor DF was isolated from Manduca sexta. This polypeptide has 41 amino acids which were sequenced, and a DNA sequence was deduced from the amino acid sequence. Polypeptides having insect diuretic factor activity may be synthetically produced and used as an insecticide as it disrupts the normal balance of fluids. DNA sequences encoding a polypeptide having diuretic factor activity may be contransfected with NPV virus DNA to form a recombinant hybrid baculovirus having insecticide activity.
申请公布号
EP0359714(A2)
申请公布日期
1990.03.21
申请号
EP19890810675
申请日期
1989.09.12
申请人
SANDOZ AG;SANDOZ-PATENT-GMBH
发明人
KATAOKA, HIROSHI;KRAMER, STEVEN JAN;MAEDA, SUSUMU;ROTER, ALAN HARRIS;SCHOOLEY, DAVID ALLAN;TROETSCHLER, RUTH GENE