发明名称 |
Topically active steroidal anti-inflammatory agents |
摘要 |
Introduction of a C-12 substituent and especially a beta C-12 substituent into glucocorticoids improves their usefulness as topical antiinflammatories by increasing their topical activity relative to their systemic activity, thus reducing systemic side effects such as adrenal suppression.
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申请公布号 |
US4910192(A) |
申请公布日期 |
1990.03.20 |
申请号 |
US19870128980 |
申请日期 |
1987.12.04 |
申请人 |
SRI INTERNATIONAL |
发明人 |
AVERY, MITCHELL A.;TANABE, MASATO;YASUDA, DENNIS;DETRE, GEORGE |
分类号 |
A61K31/57;A61K31/58;C07J5/00;C07J61/00;C07J71/00;C07J73/00 |
主分类号 |
A61K31/57 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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