| 发明名称 |
Peptide derivatives |
| 摘要 |
The invention concerns pharmaceutically useful trifluoromethyl ketone substituted di-, tri- and tetra-peptide derivatives of the formulae Ia, Ib, Ic set out hereinafter, and salts thereof, which are inhibitors of human leukocyte elastase. Also described herein are pharmaceutical compositions containing a peptide derivative and processes and intermediates for use in the manufacture of the peptide derivatives.
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| 申请公布号 |
US4910190(A) |
申请公布日期 |
1990.03.20 |
| 申请号 |
US19870005538 |
申请日期 |
1987.01.20 |
| 申请人 |
ICI AMERICAS INC. |
发明人 |
BERGESON, SCOTT H.;EDWARDS, PHILIP D.;SCHWARTZ, JOHN A.;SHAW, ANDREW;STEIN, MARK M.;TRAINOR, DIANE A.;WILDONGER, RICHARD A.;WOLANIN, DONALD J. |
| 分类号 |
A61K31/40;A61K31/401;A61K31/4025;A61K31/44;A61K31/4409;A61K31/4418;A61K31/4427;A61K31/4433;A61K31/535;A61K38/00;A61K38/55;A61P9/10;A61P11/00;A61P29/00;A61P43/00;C07C205/02;C07C205/26;C07C205/43;C07D207/16;C07D213/26;C07D333/00;C07D401/12;C07D403/12;C07D409/12;C07K1/113;C07K5/04;C07K5/06;C07K5/08;C07K5/093;C07K14/81;C12N9/99 |
主分类号 |
A61K31/40 |
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