摘要 |
Compounds of the formula: <IMAGE> in which Z is <IMAGE> +TR <IMAGE> wherein X is alkylene, ethanylene or alkylidene; Q is alkylene, alkylidene, <IMAGE> or Q, taken together with the carbon atoms to which it is attached forms a benzene ring or a substituted benzene ring, in which said substituents are -OH, -OCH3, alkyl, halo, -CF3, -NH2, monoalkylamino, dialkylamino or alkanoylamino; R1 is hydrogen or alkyl; R2 and R3 are, independently, hydrogen or alkyl or taken together with the carbon atoms to which they are attached, they form a cycloalkane or cycloalkene ring; m is one of the integers 2-5; R4 is hydrogen, hydroxy, cyano, alkyl, alkoxy, halo, amino, alkylamino, phenylamino, tolylamino, xylylamino, mesitylamino, methoxyphenylamino, or halophenylamino; and the dotted lines represent optional unsaturation; or a pharmaceutically acceptable salt thereof.
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