7-OXABICYCLOHEPTANE SUBSTITUTED OXA PROSTAGLANDIN ANALOGS

摘要

HA342 7-OXABICYCLOHEPTANE SUBSTITUTED OXA PROSTAGLANDIN ANALOGS 7-Oxabicycloheptane substituted oxo prostaglandin analogs are provided having the structural formula wherein R1 is lower alkyl, aryl, aralkyl, cycloalkyl or cycloalkylalkyl, A is -CH=CH- or -(CH2)2-, n is 1 to 4, m is 1 to 8, and 2 is wherein R3 is lower alkyl, aryl or arylalkyl; or wherein R4 is H or lower alkyl and including all stereoisomers thereof.