PROCESS FOR PREPARING 4-(BICYCLIC HETERO-CYCLYL)-METHYL AND HETERO-PIPERIDINES DERIVATIVES

摘要

4-[(di-cyclic heterocyclyl)-methyl and -hetero piperidine derivatives (I) are new. In (I), A1=A2=A3=A4 is selected among - CH=CH-CH=CH-, -N=CH-CH=CH-, -CH=N-CH=CH-, -CH=CH-N=CH-, and -CH=CH- CH=N- substituted for halo, lower-alkyl, lower-alkyloxy, trifluoromethyl or hydroxy; R1 is hydrogen, cycloalkyl or lower alkyl; R2 is hydrogen or lower alkyl; B is CH2, O, S, SO or SO2; L is L1-CrH2r-T-Cs-H2s-.