发明名称 |
PARATHION HYDROLASE ANALOGS AND METHODS FOR PRODUCTION AND PURIFICATION |
摘要 |
The present invention provides a novel gene encoding DNA sequence for the expression of parathion hydrolase and an analog thereof, and methods for preparing such compounds. In a particularly preferred embodiment, the present invention relates to a parathion hydrolase gene encoding sequence in which twenty-eight amino acids are deleted from the N-terminal amino acid sequence of parathion hydrolase. The novel gene encoding parathion hydrolase encoding sequence is useful for production of the mature or processed parathion hydrolase and a methionine (-1) analog thereof. |
申请公布号 |
WO9002177(A1) |
申请公布日期 |
1990.03.08 |
申请号 |
WO1989US03721 |
申请日期 |
1989.08.25 |
申请人 |
AMGEN INC. |
发明人 |
SERDAR, CUNEYT, M.;MURDOCK, DOUGLAS |
分类号 |
C12N15/09;C07K14/00;C07K14/195;C07K14/41;C12N1/21;C12N9/16;C12R1/125;C12R1/19;C12R1/38;C12R1/40;C12R1/865;(IPC1-7):C12N15/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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