| 摘要 |
PURPOSE:To easily obtain the subject compound useful for controlling the damage of soybean cyst nematode in high yield by chemical process by using a specific compound as a raw material, reacting with CO in the presence of a specific catalyst and tributylamine and hydrolyzing the product. CONSTITUTION:A compound of formula I is made to react with magnesium thioureide-CO2 complex and then with a compound of formula II. The reaction product is cyclized, oxidized, reacted with potassium t-butoxide and dehydrated. The allyloxycarbonyl group is removed before or after the dehydration process and the dehydration product is reacted with NaH and phenyltrifluimide to obtain the compound of formula III to be used as a raw material. The compound is reacted with CO in a solvent (e.g., aqueous solution of N,N- dimethylformamide) in the presence of palladium diacetate and 1,1'-bis(diphenylphosphino)ferrocene catalyst and tributylamine under heating and the resultant compound of formula IV is hydrolyzed with sodium methoxide, etc., in methanol to obtain the objective compound of formula V. |
