发明名称 Triazole antifungal agents.
摘要 <p>The invention provides antifungal agents of the formula:- &lt;CHEM&gt; and their pharmaceutically acceptable salts, wherein R is phenyl optionally substituted by 1 to 3 substituents each independently selected from halo and CF3; R&lt;1&gt; is C1-C4 alkyl; R&lt;2&gt; is H or C1-C4 alkyl; and "Het", which is attached to the adjacent carbon atom by a ring carbon atom, is selected from pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl and triazinyl, "Het" being optionally substituted by C1-C4 alkyl, C1-C4 alkoxy, halo, CF3, CN, NO2, NH2, -NH(C1-C4 alkanoyl) or -NHCO2(C1-C4 alkyl).</p>
申请公布号 EP0357241(A1) 申请公布日期 1990.03.07
申请号 EP19890307920 申请日期 1989.08.03
申请人 PFIZER LIMITED;PFIZER INC. 发明人 DICKINSON, ROGER PETER, DR.;RICHARDSON, KENNETH, DR.
分类号 C07D401/06;A61K31/34;A61K31/41;A61K31/4196;A61K31/44;A61K31/4427;A61K31/443;A61K31/495;A61K31/50;A61K31/53;A61P17/00;A61P31/04;A61P31/10;C07D213/02;C07D213/06;C07D213/30;C07D213/50;C07D237/08;C07D237/10;C07D237/12;C07D239/26;C07D239/30;C07D241/12;C07D249/08;C07D401/10;C07D403/06;C07D403/10;C07D405/06;C07D521/00 主分类号 C07D401/06
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