发明名称 Novel trifluorinated vitamin D3 intermediates
摘要 26,26,26-Trifluoro-1 alpha ,25-dihydroxy-cholecalciferol, and the 25R or 25S epimer thereof, are described, as well as processes and intermediates utilized to prepare the same, as well as pharmaceutical compositions containing the same. 26,26,26-trifluoro 1 alpha ,25-dihydroxycholecalciferol and the 25R or 25S epimer thereof are useful agents in the treatment of disease states such as osteoporosis, osteodystrophy and leukemia.
申请公布号 US4906785(A) 申请公布日期 1990.03.06
申请号 US19860821299 申请日期 1986.01.22
申请人 HOFFMANN-LA ROCHE INC. 发明人 BAGGIOLINI, ENRICO G.;PIZZOLATO, GIACOMO;TRUITT, GARY A.;USKOVIC, MILAN R.
分类号 C07C45/30;C07C49/513;C07C401/00;C07F7/18 主分类号 C07C45/30
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