| 摘要 |
A method of preventing or treating posttraumatic nervous injuries by administering a compound of the formula: <IMAGE> I wherein R1 is hydrogen, a lower alkyl group, cyclohexyl or benzyl; Z is one of the groups <IMAGE> if Z is a group (a), R2 and R3 together represent an additional bond between the carbon atoms bearing them, or if Z represents a group (b), R2 is hydrogen; R4 is hydrogen or lower alkyl; R5 is hydrogen, lower alkyl or phenyl, and R6 is hydrogen or methyl. Hydrates or pharmaceutically acceptable acid addition salts may also be used in the method. Pharmaceutical compositions used in this method containing such compounds in a prophylactically or therapeutically effective amount may be administered by infusion, injection, orally, perorally, rectally, percutaneously or other route.
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