PROCESS FOR THE PREPARATION OF TRICYCLIC LACTAMS

摘要

This invention relates to conformationally rigid sulfur containing tricyclic lactams, of formula wherein R is hydrogen, alkyl, or arylalkyl, and R' is hydrogen or -COR, to the intermediates and processes useful for their preparation, and to their pharmacological effects in inhibiting angiotensin converting enzyme, in treating reperfusion injury and in treating heart-failure.