发明名称 GUANIDINIUM SALTS OF ASPARTIC ACID
摘要 1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE The L-arginine salt of N-(D)-{[2-(2,6-dichlorophenylamino)phenyl]acetyl}aspartic acid, represented by the formula see diagramm : EP0253293,P9,F3 in which AmH (anion) represents the cation derived from L-arginine Am of the formula see diagramm : EP0253293,P10,F1 and its hydrates. 1. Claims for the Contracting States : AT, ES, GR A process for the manufacture of the L-arginine salt of N-(D)-{[2-(2,6-dichlorophenylamino)phenyl]acetyl}aspartic acid, represented by the formula see diagramm : EP0253293,P11,F1 in which AmH (anion) represents the cation derived from L-arginine Am of the formula see diagramm : EP0253293,P11,F2 and its hydrates, characterised in that L-arginine is reacted with N-(D)-{[2-(2,6-dichlorophenylamino)phenyl]acetyl}aspartic acid L-arginine salt in the form of the trihydrate is measured.
申请公布号 EP0253293(B1) 申请公布日期 1990.02.28
申请号 EP19870109865 申请日期 1987.07.08
申请人 CIBA-GEIGY AG 发明人 BASCHANG, GERHARD, DR.;SALLMANN, ALFRED, DR.
分类号 A61K31/195;A61K31/198;A61K31/205;A61P25/04;A61P29/00;C07C67/00;C07C233/12;C07C233/47;C07C237/20;C07C239/00;C07C279/14;C07K5/02 主分类号 A61K31/195
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