发明名称 |
Process for preparing antibiotics D788-7. |
摘要 |
<p>This invention relates to a process for preparing an antibiotic D788-7 (II) wherein, after culturing carborubicin-producing bacteria, the obtained culture liquid is extracted in acidic conditions while stirring to be adsorbed to synthetic resin, followed by desorption from the resin and elution with acetone and the resulting acetone solution containing carborubicin is converted into an antibiotic D788-7 by photo radiation, for obtaining D788-7 in the purified form from the reaction solution. The production yield for D788-7 is extremely high and its use as an antitumor agent can be made possible. <CHEM> r</p> |
申请公布号 |
EP0355843(A2) |
申请公布日期 |
1990.02.28 |
申请号 |
EP19890115711 |
申请日期 |
1989.08.25 |
申请人 |
SANRAKU INCORPORATED |
发明人 |
YOSHIMOTO, AKIHORO;JODO, OSAMU SANRAKU HODOGAYARYO;WATANABE, YOSHIO;OKAMOTO, ROKURO;TAKEUCHI, TOMIO |
分类号 |
C12P19/56;A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61P35/00;C07H15/252;C12R1/465 |
主分类号 |
C12P19/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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