17B-N-MONOSUBSTITUTED CARBAMOYL OR-17B-ACYL-4-AZA-5L-ANDROST-1-EN-3-ONES, AND ITS PREPARATION PROCESS

摘要

4-Aza-steroids of formula (2) and (I') are prepared. In the formulas, R is H, mekhyl or ekhyl; R' is C1-12 alkyl or hydrocarbon radical; R' is H or methyl; R" h or beta-methyl; R"' is H or alph- or beta- methyl; R1' is C1-12 alkyl, aralkyl or 4-pyridil. (I) are potent anti-androgens and are useful for treating acne vulgaris, seborrhea and female hirsutism.