发明名称 TETRAHYDRO-BENZO (E) ISOINDOLINES
摘要 A compd. of the 3a, 4, 5, 9b-tetrahydrobenzo[e -isoindoline[I; R, R1, R2 are independently selected from H, OH, C1-3 alkoxy, or R and R1, or R1 and R2 can be taken together to form methyleneodioxy or ethylenedioxy bridge; with proviso that at least one of R, R1 or R2 must be other than H; and R3 is H, C1-4 alkyl, aralkyl, 1,4- benzodioxane), useful as antihypertensive agents and their intermediates, is prepd. by reduction of a compd. of 1,3-dioxo-3a, 4, 5, 9b-tetrahydro-benzo [e -isoindoline (II).
申请公布号 KR900001193(B1) 申请公布日期 1990.02.28
申请号 KR19830002396 申请日期 1983.05.31
申请人 ABBOTT LABORATORIES 发明人 DEBERNAROYS JAHN F.;MCCLELLAN WILLIAM J.;CALKMAN DANIEL J.
分类号 A61K31/40;A61K31/403;A61P9/12;C07D209/56;C07D209/62;C07D209/66;C07D405/06;(IPC1-7):C07D209/62 主分类号 A61K31/40
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