发明名称 SUBSTITUTED OXADIAZOLES
摘要 Novel compounds of formula (I), processes for their preparation, and their use as pharmaceutical agents are described: <CHEM> in which X represents a group <CHEM> wherein one of Y and Z represents nitrogen and the other represents CR where R is selected from halogen, CN, OR<1>, SR<1>, N(R<1>)2, NHR<1>, NHCOR<1>, NHCOOCH3, NHCOOC2H5, NHOR<1>, NHNH2, COR<1>, COR<2>, C2-4 alkenyl, C2-4 alkynyl or C1-2 alkyl substituted with OR<1>, N(R<1>)2, SR<1>, CO2R<1>, CON(R<1>)2 or one or two halogen atoms, in which R<1> is hydrogen or C1-2 alkyl and R<2> is OR<1>, NH2 or NHR<1>; and each of p and q independently represents an integer of 2 to 4.
申请公布号 ZA8902710(B) 申请公布日期 1990.02.28
申请号 ZA19890002710 申请日期 1989.04.13
申请人 BEECHAM GROUP PLC. 发明人 MICHAEL STEWART HADLEY;BARRY SIDNEY ORLEK;PAUL ADRIAN WYMAN;HARRY JOHN WADSWORTH
分类号 A61K31/40;A61K31/435;A61K31/55;A61P25/02;A61P25/28;C07D455/02;C07D471/04;C07D471/08;C07D487/08 主分类号 A61K31/40
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