DIAZINE-ETHENYLPHENYL OXAMIC ACIDS AND THE PREPARATION PROCESS THEREOF

摘要

Diazine-ethylphenil oxamic acids of formula (I) or their pharmaceutically acceptable salt are prepd. by reacting an amine of formula (II) with oxalate halide or dialkyl oxalate, and hydrolyzing an ester. In the formulas, R1 is H or C1-4 alkyl; R2 is H, methyl, C1-4 alkoxy hydroxyl; or A is (a) or (b); R3 is H, methyl or C1-4 alkoxy; R4 is H, amino, C1-4 alkoxy or halogen. (I) have an imunological, antiinflammatory and antiallergic activity.