发明名称 |
PROCESS FOR OBTAINING ESTHERS OF 7-BETA-MALONAMIDO-7 ALPHA-METOXY-3-TETRAZOLYL THIOMETHYL-1-DETHIA-1-OXA-3-CEPHEM-4-CARBOXYLIC ACID |
摘要 |
<p>A compound represented by the formula (II) epimerizes by the action of a base and the product is precipitated for shifting the equilibrium to yield the corresponding epimer represented by the formula (I). <IMAGE> (II) <IMAGE> (I) wherein Ar is an optionally substituted aryl or heterocyclic group; Tet is an optionally substituted tetrazolyl group and B1 and B2 are each ester forming group in the field of penicillin or cephalosporin chemistry.</p> |
申请公布号 |
YU44011(B) |
申请公布日期 |
1990.02.28 |
申请号 |
YU19830001445 |
申请日期 |
1983.07.01 |
申请人 |
SHIONOGI & CO LTD |
发明人 |
NARISADA M;OHTANI M;WATANABE F |
分类号 |
C07D505/02;C07B31/00;C07B57/00;C07C67/00;C07D498/04;C07D505/00;C07D505/20;(IPC1-7):C07D498/02;A61K31/535 |
主分类号 |
C07D505/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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