PROPIONAMIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION
摘要
<p>Novel propionamidine derivatives of the formula: (I) wherein X is halogen, are disclosed, as well as a process for their preparation. The process involves reacting a 3-halopropionitrile of the formula: (III) wherein X is as defined above, with sulfamide of the formula: (II) in the presence of a hydrogen halide. The compounds of formula (I) are useful intermediates in the preparation of famotidine.</p>
申请公布号
CA1266277(A)
申请公布日期
1990.02.27
申请号
CA19860516618
申请日期
1986.08.22
申请人
RICHTER GEDEON VEGYESZETI GYAR RT.
发明人
BOD, PETER;HARSANYI, KALMAN;CSONGOR, EVA NEE AGAI;DOGSCH, ERIK;FEKECS, EVA;TRISCHLLER, FERENC;DOMANY, GYOERGY;SZABADKAI, ISTVAN;HEGEDUES, BELA