发明名称 OLIGOSACCHARIDE HEPARIN FRAGMENTS AS INHIBITORS OF COMPLEMENT CASCADE
摘要 <p>There are disclosed oligosaccharide compounds having heparin-like anticomplement activity and reduced anticoagulant activity as compared with heparin on a weight or molar basis. The oligosaccharide compounds have at least 5 and no greater than 25 saccharide units. The oligosaccharides can have an even number of saccharide units with a terminus nonreducing sugar, or an odd number of saccharide units without a terminus nonreducing sugar. There are also disclosed anticomplement pharmaceutical compositions with reduced anticoagulant side effect activity and a process for preparing the oligosaccharide compounds.</p>
申请公布号 WO1990001501(A1) 申请公布日期 1990.02.22
申请号 US1989003312 申请日期 1989.08.01
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