发明名称 TRIPEPTIDE RENNIN INHIBITOR HAVING N-TERMINAL CARBAMOYL OR ACYL GROUP
摘要 Tripeptide enzyme inhibitors of the formula: <CHEM> which have N-terminal carbamoyl or acyl functional groups and analogs thereof, which inhibit renin and are useful for treating various forms of renin-associated hypertension and congestive heart failure; compositions containing these renin-inhibitory peptides, optionally with other antihypertensive agents; and methods of treating hypertension or congestive heart failure or of establishing renin as a causative factor in these problems which employ the novel tripeptides.
申请公布号 JPH0240398(A) 申请公布日期 1990.02.09
申请号 JP19890155939 申请日期 1989.06.20
申请人 MERCK & CO INC 发明人 UIRIAMU AARU SHIEEN
分类号 C12N9/99;A61K38/55;A61P5/38;A61P9/00;A61P9/12;C07K5/02;C07K5/06;C07K14/81 主分类号 C12N9/99
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