| 发明名称 |
TUMOR NECROSIS FACTOR(TNF)INHIBITORY PROTEIN AND ITS PURIFICATION |
| 摘要 |
Tumor Necrosis Factor (TNF) Inhibitory Protein is isolated and substantially purified. It has the ability to inhibit: (a) the binding of TNF to its receptors, and (b) the cytotoxic effect of TNF. TNF Inhibitory Protein, salts, functional derivatives and active fractions thereof and mixtures of any of the foregoing can be used to antagonize the deleterious effects of TNF. |
| 申请公布号 |
ZA8806818(B) |
申请公布日期 |
1990.01.31 |
| 申请号 |
ZA19880006818 |
申请日期 |
1988.09.13 |
| 申请人 |
YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED |
发明人 |
DAVID WALLACH;HARTMUT ENGELMANN;DAN ADERKA;MENACHEM RUBINSTEIN |
| 分类号 |
C12N15/09;A61K38/00;A61P9/00;A61P37/06;A61P37/08;C07H21/04;C07K1/16;C07K1/20;C07K14/00;C07K14/47;C07K14/52;C07K14/525;C07K14/715;C07K16/00;C07K16/18;C07K16/24;C07K16/28;C07K19/00;C12P21/00;C12P21/08;C12R1/19 |
主分类号 |
C12N15/09 |
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