QUINOLIZINONE COMPOUND, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

摘要

A compound of the formula: …… wherein… R<1> is carboxy, amidated carboxy, cyano, thiocarbamoyl or tetrazolyl group;… R<7> is hydrogen or aryl;… R<2> is hydrogen, hydroxy, lower alkyl or lower alkoxy;… R3 is hydrogen, hydroxyl, lower alkyl, lower alkoxy, lower alkenyloxy, aryl which may have suitable substituent(s), arylthio, aroyl, ar(lower)alkyl, arenesulfonyl, arylamino which may have a suitable substituent or aryloxy; and… R<2> and R<3> can be located at any place on the quinolizinone ring and can be linked together to form -CH2CH2CH2-, -CH = CH- or-CH = CH-CH = CH-;… and pharmaceutically acceptable salts thereof, processes for preparing them and pharmaceutical compositions comin prising them in association with the pharmaceutically acceptable, substantially non-toxic carrier or excipient.