发明名称 |
Pharmaceutical compositions |
摘要 |
A pharmaceutical tablet is described which comprises a tablet core containing the antibiotic cefuroxime axetil and a film coat which serves to mask the bitter taste of the cefuroxime axetil upon oral administration. It has been found that conventional film-coated tablets reduce the bioavailability of cefuroxime axetil and the invention overcomes this by control of the film coat rupture time and use of a tablet core which disintegrates immediately following rupture of the film coat.
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申请公布号 |
US4897270(A) |
申请公布日期 |
1990.01.30 |
申请号 |
US19880291364 |
申请日期 |
1988.12.30 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
DEUTSCH, DAVID S.;ANWAR, JAMSHED |
分类号 |
A61K9/20;A61K9/28;A61K9/30;A61K9/32;A61K9/36;A61K31/545;C07D501/34 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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