| 摘要 |
Antihypertensive phosphate derivatives having the following formula are described: <IMAGE> FORMULA 1 wherein X is selected from the group consisting of a phenyl radical substituted at any position with a C1-C20 branched or straight chain alkoxy or benzyloxy and optionally substituted at any other positions with one or more groups consisting of C1-C15 branched or straight chain alkyl, C1-C15 branched or straight chain alkoxy and halogen, and a naphthalene radical substituted at any position with a C1-C20 branched or straight chain alkoxy or benzyloxy and optionally substituted at any other positions with one or more groups consisting of C1-C15 branched or straight chain alkyl, C1-C15 branched or straight chain alkoxy and halogen; T is selected from the group consisting of hydrogen and <IMAGE> wherein R1 is selected from the group consisting of hydrogen, C1C4 branched or straight chain alkyl, C1-C4 branched or straight chain alkoxy and C1-C4 branched or straight chain alkylamino; Y is selected from the group of bivalent radicals consisting of -(CH2)p- and -(CHR)p-, wherein p is an integer from 2 to 10 and the moiety -(CHR)p- represents an alkylene chain substituted with one or more C1-C8 alkyl groups or phenyl groups; Z is selected from the group consisting of <IMAGE> wherein q is an integer from 4-7 and R2 may be the same or different and is selected from the group consisting of hydrogen and C1-C4 branched or straight chain alkyl.
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