PROCESS FOR PREPARING 3-(PYRID-4-YL)PROPANOIC ACID DERIVATIVES

摘要

11833 A process for preparing compounds of the formula (II): (II) and salts thereof, wherein R1 is protected hydroxy, which comprises reacting an anion of the formula (III) : (III) wherein R1 is as hereinbefore defined, with a compound of the formula (IV) : X-CH2C0?M+ wherein X is a leaving group and M is a counterion, and if desired interconverting an acid of the formula (II) with a salt thereof. The products are intermediates in the preparation of histamine antagonists.