发明名称 |
SYNTHETIC HIV PROTEASE GENE AND METHOD FOR ITS EXPRESSION |
摘要 |
The invention is a synthetic DNA sequence for encoding a specific enzyme or protease. The protease is essential for the completion (replication) of an infective human immunodeficiency virus (HIV). The invented gene is desirable for the expression of the protease by recombinant methodology in prokaryotic and/or eukaryotic cells and the production of a commercially desirable amount of the protease for biochemical and physical characterization, necessary to find effective inhibitor of the protease, and thereby to block the production of infectious human immunodeficiency virus (HIVs). |
申请公布号 |
WO9000556(A1) |
申请公布日期 |
1990.01.25 |
申请号 |
WO1989US02996 |
申请日期 |
1989.07.13 |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH |
发明人 |
LOUIS, JOHN, M.;OROSZLAN, STEPHEN;MORA, PETER, T. |
分类号 |
C12N15/09;A61K38/00;C07H21/04;C12N1/21;C12N9/50;C12N15/57;C12R1/19;(IPC1-7):C07H15/12;C12N9/48;C12N1/20;C12N15/00 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|