发明名称 SYNTHETIC HIV PROTEASE GENE AND METHOD FOR ITS EXPRESSION
摘要 The invention is a synthetic DNA sequence for encoding a specific enzyme or protease. The protease is essential for the completion (replication) of an infective human immunodeficiency virus (HIV). The invented gene is desirable for the expression of the protease by recombinant methodology in prokaryotic and/or eukaryotic cells and the production of a commercially desirable amount of the protease for biochemical and physical characterization, necessary to find effective inhibitor of the protease, and thereby to block the production of infectious human immunodeficiency virus (HIVs).
申请公布号 WO9000556(A1) 申请公布日期 1990.01.25
申请号 WO1989US02996 申请日期 1989.07.13
申请人 THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH 发明人 LOUIS, JOHN, M.;OROSZLAN, STEPHEN;MORA, PETER, T.
分类号 C12N15/09;A61K38/00;C07H21/04;C12N1/21;C12N9/50;C12N15/57;C12R1/19;(IPC1-7):C07H15/12;C12N9/48;C12N1/20;C12N15/00 主分类号 C12N15/09
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