发明名称 PROCESS FOR THE PREPARATION OF P-ACYLAMINOBENZAMIDES
摘要 P-acylaminobenzamides of formula (I) and their pharmaceutically acceptable acid addn. salts. are prepd. by reacting cpds. of formula (II) with amine of formula R8R9NH. In the fromulas, R is R8R9N-alk-; R8 and R9 are each H, C1-6 alkyl or C3-7 cyclo alkyl ; alk is divalent org. radical derived from C1-6 aliphatic hydrocarbon ; R'1= bromo- or chloro-substd. C1-6 alkyl ; R2,R3,R4,R5,R6 and R7 are each H or methyl ; n=0 or 1. (I) are useful for treating convulsion in mammals.
申请公布号 KR900000275(B1) 申请公布日期 1990.01.24
申请号 KR19860007213 申请日期 1986.08.29
申请人 ELI LILLY AND CO. 发明人 ROBERTSON, DAVID W.;BEEDLE, EDWARD E.
分类号 A61K31/165;A61P25/08;C07C67/00;C07C231/00;C07C231/02;C07C237/42;C07D295/15;C07D295/20;(IPC1-7):C07C235/42 主分类号 A61K31/165
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