发明名称 |
Novel esters of estramustine. |
摘要 |
<p>The present invention concerns novel compounds having the general formula <CHEM> wherein R<1>, R<2> and R<3> are selected from the group consisting of hydrogen or lower alkyl having 1-4 carbon atoms, wherein R<2> and R<3> together with the N atom can also form a ring having 2-5 carbon atoms and wherein n is 0, 1 or 2, and pharmaceutically acceptable salts thereof. The compounds according to the invention are useful as anticancer agents.</p> |
申请公布号 |
EP0351561(A1) |
申请公布日期 |
1990.01.24 |
申请号 |
EP19890111062 |
申请日期 |
1989.06.19 |
申请人 |
PHARMACIA AB |
发明人 |
HANSEN, BERTIL VALDEMAR;GUNNARSSON, PER-OLOV GUNNAR;MOLLBERG, HENRI RENE;JOHANSSON, SVEN-AKE |
分类号 |
A61K31/565;A61K31/56;A61P35/00;A61P43/00;C07J1/00;C07J41/00 |
主分类号 |
A61K31/565 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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