| 摘要 |
<p>NEW MATERIAL:A peptide (salt) shown by the formula. USE:A memory enhancer or an agent for preventing failure of memory. PREPARATION:For example, a benzhydrylamine type resin is used as a solid- phase carrier, the resin is subjected to coupling reaction with an amino acid containing alpha-group protected with Boc(tert-butoxycarboxyl) group, etc., according to order to amino acid sequence of peptide by starting from amino acid of C-end and successively adding to N-end, then the amino-protecting group is treated with trifluoroacetic acid, etc., these operations are repeated and a protective peptide resin is synthesized. Finally the peptide is separated from the resin by HF treatment and the whole protecting groups are removed to give a novel peptide having an amino acid sequence shown by the formula.</p> |
