摘要 |
<p>NEW MATERIAL:A compound expressed by formula I (R<1> to R<4> are H or OH- protecting group; R<5> is H or amino-protecting group). EXAMPLE:A compound expressed by formula II. USE:An antitumor and antiviral agents available in high yield at a low cost in a short process. PREPARATION:A compound expressed by formula III (R<6> to R<9> are OH- protecting group) is reacted with adenine having protected amino group in the presence of potassium fluoride or sodium hydride to afford the compound expressed by formula I (groups R<1> to R<4> are OH-protecting group; group R<5> is amino-protecting group).</p> |