发明名称 NUCLEOSIDE CARBOCYCLIC HOMOLOG AND PRODUCTION THEREOF
摘要 <p>NEW MATERIAL:A compound expressed by formula I (R<1> to R<4> are H or OH- protecting group; R<5> is H or amino-protecting group). EXAMPLE:A compound expressed by formula II. USE:An antitumor and antiviral agents available in high yield at a low cost in a short process. PREPARATION:A compound expressed by formula III (R<6> to R<9> are OH- protecting group) is reacted with adenine having protected amino group in the presence of potassium fluoride or sodium hydride to afford the compound expressed by formula I (groups R<1> to R<4> are OH-protecting group; group R<5> is amino-protecting group).</p>
申请公布号 JPH0217190(A) 申请公布日期 1990.01.22
申请号 JP19880166523 申请日期 1988.07.04
申请人 TAISHO PHARMACEUT CO LTD 发明人 KITAGAWA ISAO
分类号 C07D473/34;A61K31/52;A61P31/12;A61P35/00 主分类号 C07D473/34
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