Monoclonal antibody NUH2 capable of inactivating motility of sperm, antigen defined by said monoclonal antibody and methods of using said monoclonal antibody and antigen.

摘要

Monoclonal antibody NUH2 produced by a hybridoma having ATCC deposit no. HB 9762. An isolated antigen capable of specifically binding to anti-human sperm antibodies including NUH2 and comprising at least an epitope having a sialyl I structure, and any analogues derived from said antigen. Methods of using the monoclonal antibody and antigen for contraception and treating infertility in human females.