N-(L-ASPARTYL)AMINO ALCOHOL DERIVATIVES AND SWEETENER CONTAINING THE SAME

摘要

(2R,3R)-3-N-(L-aspartyl)amino-1-(1-methyl-2-norbornyl)-2-butanol and (2R,3R)-3-N-(L-aspartyl)amino-1-(3-methyl-2-norbornyl)-2-butanol are novel sweeteners. They are sweeter than other of the 3-methyl-2-norbonyl isomers and are stable in acidic aqueous solutions, are highly useful as a powder or solution, as a sweetener for various foods, beverages or medicines. Two reaction schemes for their synthesis, from norbornanone or (+)-camphor-10-sulfonic acid, are given.