摘要 |
<p>PURPOSE:To detect a biocomponent with high sensitivity by bringing a material which reacts with the other section of a material to be detected into contact with top of the material to be detected which is brought into contact with the surface of a biodetecting device and amplifying the change in various densities of light interference colors, etc. CONSTITUTION:The biocomponent detecting device is formed by laminating a light interference layer II and a material layer III which consists of a monomolecular layer and detects the biocomponent successively on a light reflecting base plate I which has substantially no irregular reflection. The soln. of the material IV to be detected is brought into contact with the surface of this device. The material V which reacts specifically with another reaction section in the material IV to be detected is further brought into reaction. This material V reacts specifically with the material IV to be detected in the section different from the section of the material layer III in the above-mentioned manner to induce an increase in film thickness on the device surface, thereby amplifying the change in the light interference colors or the change in the various densities of the reflected light. The biocomponent of a dilute concn. which is heretofore difficult to be detected is amplified with the high sensitivity and is detected in this way.</p> |