发明名称 PROCESSO PARA A PREPARACAO DE 1-INDOLILALQUIL-4-(PIRIDINIL SUBSTITUIDO)-PIPERAZINAS E DE COMPOSICOES FARMACEUTICAS QUE AS CONTEM
摘要 A compound of Formula I and the pharmaceutically acceptable acid addition salts thereof, <CHEM> wherein R<1> and R<2> are independently selected from lower, meaning C1-4, alkyl or hydrogen; R<3>, R<4>, R<8> and R<9> are independently selected from hydrogen, lower alkyl, lower alkoxy, carbamide, halogen, trifluoromethyl and thio-lower alkyl, with the proviso that R<8> and R<9> cannot both be hydrogen at the same time; A is a C5-7 cycloalkanyl or cycloalkenyl ring, or A is <CHEM> wherein n is an integer from 1 to 3 and R<5> is the same as R<1>; and R<6> and R<7> are independently selected from hydrogen, methyl or R<6> and R<7> can be taken together as a methylene bridge, useful as antidepressants.
申请公布号 PT90805(A) 申请公布日期 1989.12.29
申请号 PT19890090805 申请日期 1989.06.09
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 RONALD J. MATTSON;DAVID W. SMITH;FRANK D. YOCCA;JOSEPH P. YEVICH
分类号 C07D487/04;A61K31/44;A61K31/495;A61P25/24;A61P25/26;C07D401/12;C07D401/14;C07D487/08 主分类号 C07D487/04
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