| 发明名称 |
METHOD FOR THE PRODUCTION OF MONOCLONAL ANTIBODIES UTILIZING A GERMFREE ANIMAL |
| 摘要 |
The subject invention relates to a method for the production of monoclonal antibodies. The method utilizes an immunized germfree animal. The invention also provides a method for the use of such monoclonal antibodies, and polyclonal antibodies derived from an immunized germfree animal, for in vitro and in vivo clinical diagnostics and therapeutics. Also, the subject invention provides a fibrin-specific monoclonal antibody. |
| 申请公布号 |
WO8912690(A1) |
申请公布日期 |
1989.12.28 |
| 申请号 |
WO1989US02545 |
申请日期 |
1989.06.12 |
| 申请人 |
AMERICAN BIOGENTIC SCIENCES, INC. |
发明人 |
GARGAN, PAUL, E.;PLOPLIS, VICTORIA, A.;PLEASANTS, JULIAN, R. |
| 分类号 |
A61K38/00;A61K39/395;A61K47/48;A61K51/10;C07K16/18;C07K16/36;G01N33/531;G01N33/573;G01N33/86;(IPC1-7):C12P21/00;A61K43/00;G01N33/566;C12Q1/64;A61K45/05;C07K15/00;C07K15/04;C12N5/00 |
主分类号 |
A61K38/00 |
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